The Escalation to Critical Limb Ischemia: A Market Urgency Peripheral Artery Disease (PAD) is often viewed as a progressive, slowly developing condition, but its endgame is terrifyingly abrupt. When PAD is left untreated, it frequently escalates into Critical Limb Ischemia (CLI), the most severe and deadly manifestation of the disease. At this stage, blood flow to the extremity is so severely restricted that patients experience chronic pain even while...